Peach varieties Istikbol and Gulnoz were found to be resistant to clasterosporiosis. The incidence rate ranged from 13.0 to 45.0%, with the severity of the disease from 8.0 to 22.7%. In the fight against clasterosporiosis, the chemical method is considered the most effective. For chemical protection, it is recommended early spring triple treatment of trees in the following terms: 1 - before the buds swell; 2 - after blooming of trees; 3 - two weeks after blooming, with one of the following fungicides: Skor 250 EC (normally 0.02% suspension), Kresoxin 50% WDG. (0.02%), Topsin-M 70% WP (0.1%) and Falcon 46% EC (0.05%) against peach clasterosporiosis.