Primary aldosteronism is the most common endocrine disorder. which aldosterone production is inappropriately high for sodium status, inappropriate production of aldosterone causes hypertension, cardiovascular damage, sodium retention, suppression of plasma renin, and increased potassium excretion that excess level cause severe may lead to hypokalemia. It is commonly caused by an adrenal adenoma or hyperplasia and adrenal carcinoma or inherited conditions of familial hyperaldosteronism.