This descriptive study was conducted at teaching hospital (Diabetic Center) Gadarif State / Eastern of Sudan with an aim to study the Diabetes Mellitus (DM) and associated epidemiological factors 2019, .the sample size was 370 patients according to Richard geiger Formula, the data were collected by using the following methods, observation, interview, structure questionnaire which distributed for each patient infected with DM disease, the data were analyzed manually using Excel sheets, results depicted as tables and figures. The main result in this study showed that (63%) of the targets Resident in urban area, also reported (6%) were smoking , (12%) stopped and (82%)were not smoking , While (0.3%) were taking alcohol , (5.4%) stopped and (94.3%) not, likewise that it concluded (38%male, 30%female) were normal waist circumference and (62% male , 70% female ) were abnormal ( less & more ) waist circumference. The important recommendation in this study that Raising detection rate for DM disease in Gadarif state by Strengthen of referral system and Activation of mobile clinics and teams investigation, Providing of DM center with more medical equipment’s, Raising health awareness for patients and community with regard to DM disease.