Guna is one among Shadpadarthas, and it has its important role in Chikitsa to achieve the goal of Ayurveda i.e Dhatusamyata. The word meaning of Guna is “it is a Padartha which creates attraction”. These Gunas are present in Dravya as well as in Shareera. So it has to be understood in a proper manner, to utilize for therapeutic measure. Because, Guna is in inseparable relation with Dravya and Dravya imparts Guna in Shareera. These Gunas are found in Ahara dravya and when they come into contact with Shareera then the Pachakagni and Dhatvagni disintegrate it into Gunas and they are going to nourish particular Deha dhatu possessing similar Guna. So according to need one has to use the Aahara dravyas to maintain the Prakruta guna of Shareera. In the context of Hetu, Lingha and Chikitsa, Guna has an important and relevant role. The role of Guna is visualized in entire aspects of Ayurveda narrated in Trisutra form. So Guna is the basic pillar of Chikitsa. Gurvadi Guna (Dravyaguna / Shareerika guna) are more importance because of its pharmacological and therapeutic application. Snigdha and Ruksha are important pair of Guna. In normal state both have their role on Dosha and Dhatu level. When these Snigdha and Ruksha Guna get disturbed then they leads towards manifestation of many Vyadhis. The most of the Chikitsa aspects in clinical practice are based more on Snehana & Rukshana. Hence the main Aim of the study is to compile and analyze the Hetu, Lingha and Aoushadha aspects of Snigdha and Ruksha Guna individually with respect to Sthoulya and Vatavyadhi.