Agada tantra is defined as one among the eight branches of Ayurveda which deals with the signs , symptoms and management of poisoning , resulting from the bites of snakes , insects, worms , spiders, rodents etc and various other poisons produced by improper combinations of substances or drugs. Garavisha(~concocted poison) is mentioned as a type of visha(~poison) which is formed by the combination of two or more poisonous or non-poisonous substances, which slowly gets accumulated in the body and ultimately affects all parts of the body by vitiating all Dosha(~humor), Dhatu(~tissues), Mala(~waste products) and Srotas(~channels). Many ayurvedic formulations are mentioned for the treatment of Gara visha. Mrityupasacchedi ghrita is one among them which is explained in Bhaishajya Ratnavali. It is a form of Ghrita Kalpa (~ghee preparation), the use of Ghrita (~ghee) plays an important role in the management of Visha (~poison) condition. It’s effect cures severe poisoning and garadoshaja (~concocted poison) poisoning. It cures disorders like tamaka svasa(~bronchial asthma), kandu(~itching), mamsasada(~depletion of muscles) and visamjna(~fainting).It also cures poisoning caused by the bite of snake , poisonous insects , rats and spiders. Mrityupasacchedi ghritam is a formulation that has a combination of many herbs which are easily accessible and have a simple method of preparation . Hence an effort is made to review the Mrityupasacchedi ghritam for Vishahara (~anti-poison) property.