Grapes (Vitis vinifera) are commonly known grape species that belong to the Vitis genus in the Vitaceae family and come from western Asia and southern Europe. Visit Vinifera (Grapes) contain valuable phenolic components and grape byproducts are widely available low cost raw materials. They also present antioxidant, antimicrobial, anti-inflammatory or antiaging actions and can permeate through the skin barrier. These ingredients of Vitis Vinifera are reported to have many functions in cosmetics, most frequently as skin conditioning agents. Some of these ingredients are reported to function as antioxidants, flavoring agents and many other activities. The demand of natural skin care products is steadily growing since consumers perceive them as safe. Currently, cosmetic manufacturers are focusing their efforts on developing innovative natural products to address skin-care, thus meeting consumers’ needs of healthy appearance and well-being. This review presents an overview of the application of phenolic compounds from grape products and byproducts as sources of natural ingredients for cosmetics i.e. in skin care.