Chronic kidney disease (CKD) is a long-term pathological condition with loss of function over several months to years. In the present study the CKD risk assessment in diabetic, hypertension is assessed using CKD assessment questionnaire, GFR and other biochemical parameters. In the present study 1270 patients were identified with risk of CKD in which 250 patients were dropped due to various reasons, 1020 patients data was studied and analyzed as per our objectives. The findings suggest that the CKD risk is more in elder patients than younger patients with diabetics and hypertension. Females are at more risk to CKD when compared to males. When BMI was analyzed the Female Obese patients are 90% significant risk to CKD followed by obese male. 95% significant risk was observed for CKD in house wives, Govt employees followed by Private employees with sedentary life style. Family history of CKD in diabetic and hypertension was analyzed then there is no significant difference among them. When education status was analyzed in hypertension and diabetes patients then there is no significant difference among them. when GFR was analyzed then 95% significant risk was observed in stage-1 vs stage-3A, 95% significant risk was observed in stage-1 Vs stage-3B and 99% significant risk was observed between stage-1 Vs stage-5. It is concluded that increased age are at more risk, in Gender Females are more risk than males, in BMI higher BMI are more risk, Family history was Independent ,in Occupation house wives are more risk , in GFR – Stage 5 are more risk and in Social history was Independent.