The purpose of the study is to study the foreign policy activities of the Republic of Uzbekistan to improve the mechanism of multilateral interaction with the Shanghai Cooperation Organization. In this regard, it is necessary to solve the following research tasks: - to conduct a political analysis of theoretical approaches to the study of the processes of regionalization and integration; identify the specifics of the region of education in Central Asia and its influence on the formation of the foreign policy of the Republic of Uzbekistan; consider the formats and potential for the development of international cooperation and reveal the political role and influence of the Republic of Uzbekistan on the development of the SCO; to determine, on the basis of Uzbekistans initiatives, ways to improve multilateral cooperation within the framework of the SCO; develop specific proposals and formulate recommendations of the Republic of Uzbekistan aimed at increasing the efficiency of the SCO.