The Increasing awareness about the health, food safety, and environmental sustainability has significantly increased consumer interest in organic food products, particularly in developing countries. This study aims to examine the major determinant factors that are influencing consumers’ purchase intention towards organic food products and to analyze the moderating role of consumer knowledge through a comprehensive review of existing literatures. The research adopts a qualitative and descriptive approach based on secondary data collected from peer-reviewed journal articles, books, and scholarly publications available in academic databases such as Scopus, Science Direct, Springer, Taylor & Francis, and Google Scholar. Relevant studies published between 2008 and 2026 were systematically reviewed and analyzed using a thematic analysis approach to identify key determinants of organic food purchasing behavior. The findings from the literature indicate that factors such as health consciousness, environmental concern, consumer attitude, and perceived product quality play a significant role in influencing consumers’ intention to purchase organic food products. The review also highlights that consumer knowledge regarding organic food production methods, certification standards, and health benefits strengthens consumers’ understanding and confidence in organic products. Furthermore, consumer knowledge is identified as an important moderating factor that can influence the relationship between these determinants and purchase intention. The study contributes to the existing literature by synthesizing previous research findings and providing a comprehensive understanding of the drivers of organic food consumption in developing countries. The findings also offer useful implications for policymakers, marketers, and organic food producers to promote awareness and develop effective strategies for encouraging sustainable food consumption.