The investment climate significantly impacts the development of entrepreneurship, serving as a critical determinant of economic growth and innovation. This paper examines the dynamic relationship between the investment climate and entrepreneurial activities in Uzbekistan, a nation that has undergone extensive economic reforms aimed at fostering a favorable business environment. Through an analysis of institutional reforms, foreign direct investment (FDI) trends, government initiatives, and the emergence of diverse entrepreneurial ventures, the study highlights the profound influence of investment policies on entrepreneurship. The findings suggest that Uzbekistans efforts to improve its regulatory and economic landscape have been pivotal in stimulating entrepreneurial initiatives, though challenges remain in achieving uniform development across all regions and sectors. The paper concludes that sustained improvements in the investment climate are essential for nurturing entrepreneurship, which in turn can propel Uzbekistan towards enhanced economic diversification and resilience. This study contributes to the broader discourse on how emerging economies can leverage policy frameworks to bolster entrepreneurial growth and economic stability.