The problem of duodenal ulcer (DU) in children attracts special attention, as it is very common, the clinical features are both bright and asymptomatic with a high probability of developing serious complications (ulcer bleeding, perforation, perforation) In the formation of duodenal ulcer intestines in children play the main role: neuropsychic, endocrine, hereditary-constitutional factors, drug and toxic effects, food allergies, eating disorders and great importance is attached to the infectious agent Helicobacter pylori. In children and adolescents, there is a tendency to an asymptomatic course of the disease, and in connection with this, cases of hospitalization of children with complications such as bleeding, perforation, and pyloric stenosis without any clinical manifestations have become more frequent. Also, a feature of the disease in adolescents is the localization of the ulcer in its upper part (95%) up to 1 cm in size, occasionally there are ulcers of large sizes from 3 to 6 cm. Often the disease occurs with frequent prolonged exacerbations and in a more severe form, which contributes to the development of complications. Conducting active medical examination and rehabilitation of children with this pathology reduces the likelihood of relapses and complications of the disease.