A quantitative approach using pre-experimental one group pre-test post-test design. 60 adolescent girls were selected using non probability convenient sampling adolescent girls at selected Schools of Mandi Gobindgarh, Punjab. Structured multiple choice questionnaire on demographic variables and knowledge regarding polycystic ovarian syndrome, are used for data collection. Information Education and Communication on Polycystic Ovarian Syndrome was given for 45 minutes on the second day. After the Information Education and Communication, Majority of 86.7% of the adolescent girls had adequate knowledge, moderate Knowledge observed on the 11.7% from adolescent girls and only 1.7% had inadequate knowledge. Analysis used paired ‘t’ test found significant value at p< 0.05 level