This article presents the results of identifying the types of weeds spread in the fields where winter wheat is cultivated in the irrigated lands of the southern, central and northern regions of the Republic of Karakalpakstan. 16, 17, 15 families, 55, 46, 47 species, 63, 53, 52 types of weeds were detected in the southern region Amudarya, Khojeyli in the center, and Chimboy in the north, respectively.