Lead poses the greatest threat to human health from environmental exposure. Because of its significant physicochemical characteristics, it has been helpful throughout history. It is a typical, significant, and perhaps hazardous metal that is present in our surroundings. In Ayurveda, lead is also referred to as a poisonous metal. Science and authentic Ayurveda scriptures are used to acquire data on lead poisoning. Ayurveda, on the other hand, processes numerous toxins using a variety of methods that eliminate their harmful properties, making them potent enough to be used as a very effective treatment when provided in a very small dose. Likewise, Lead can also be utilized as a very effective treatment after passing through a series of proper purifications. Ayurveda also claims that the administration of lead after improper cleansing will undoubtedly have negative effects. Additionally, it covers the potentially fatal symptoms and signs caused by the ingestion of lead that has not undergone the proper refinement. The claim that Ayurvedic treatments induce heavy metal poisoning is currently being made as a result of subpar metal processing performed by unstandardized companies prior to use in formulation. As a result, this articles primary emphasis is on the features of lead toxicity explained in the ancient works of Ayurveda.