Legal protection is all efforts made consciously by every person or government institution, private. Nurses in hospitals are an essential concern, including receiving legal protection of work safety when working there because they are at high risk of occupational accidents and illnesses. This study analyzes the Legal Protection of Health and Safety (K3) for nurses in the ICU Room (Intensive Care Unit). This type of research is qualitative research and descriptive. The research location is Royal Prima Medan Hospital from April to May 2023, with a sample size of 9 people. The data analysis used is qualitative descriptive analysis research. The results of occupational safety management (SMK3) have been made based on the rules of the occupational safety management system (SMK3) government regulation No. 50 of 2012. Royal Prima Hospital has complied with Government Regulation No. 14 of 1993 concerning implementing the Social Security System for Workers, contained in Article 2 concerning social security. Royal Prima Hospital fulfills the provisions of Work Safety Law No. 1 of 1970, regulating work safety in all workplaces, both land, sea, and air, within the territory of the Republic of Indonesia. In conclusion, Royal Prima Hospital is very concerned about the health and safety of its workforce, especially nurses as one of the medical personnel in the field of frontline services.