Science can be a challenging subject for both teachers and students. As technology in education is constantly evolving, this study aimed to explore the integration of Chatbot in an Inquiry-based approach in teaching science. This exploration measured the effect of Chatbot on the students academic achievement and science engagement. The research participants consisted of thirty (30) grade 8 students from Pagadian City Science High School for the school year 2022-2023. This exploration utilized pre-experimental research design in order to determine the improvement of the students academic achievement integrating Chatbot in an Inquiry-based approach in teaching Science. This study focused on the One Group Pre-test-Post-test design where only the experimental group is selected as the study subjects. In this study there was no control group as this design advised. By employing Mean and Paired Samples T-test, results revealed there is a very high significant difference between the level of students engagement and achievement before and after Integrating Chatbot in an Inquiry-based Approach in Teaching Science in the first, second, and third trial runs. Therefore, integrating Chatbot in an Inquiry-based approach in teaching Science is highly recommended to maximize the learning of the students. Findings of the study also provided for the better implementation of the current science curriculum, which is geared towards producing active learners through technology integration.