This article provides valuable information about the relations of the inhabitants of Ancient Khorezm with the nomadic tribes living in the lower Syrdarya basin. The article also substantiates that Khorezm’s interaction with nomadic tribes began much earlier than the Kang period according to archaeological materials. In addition, the opinions and researches of world-renowned historians and scientists on the issue of relations between Khorezm and nomadic tribes are presented.