The Clindamycin Hydrochloride is a broad spectrum cephalosporin antibiotic. It is mainly used to treatment of bacterial infections. It is a suitable candidate for controlled release administration due to its short elimination time 1 hours. The main aim of present investigation is to increase the gastric residence time by preparing floating drug delivery by using raft forming approach thereby improving bioavailability. The prepared Clindamycin Hydrochloride floating drug delivery were evaluated for hardness, weight variation, thickness, friability, drug content uniformity, total floating time, In-vitro dissolution studies and buoyancy lag time. Floating tablets were formulated using direct compression technique. Various polymers are used in the formulation they Micro crystalline cellulose used as binder, HPMC K15M, Guargum used as hydrophilic polymers, Chitosan, Sodium bicarbonate was incorporated as an effervescent substance, Sodium alginate used as viscous gel forming agent, Magnesium streate used as lubrication, talc was used as diluent. The formulated Clindamycin Hydrochloride tablet to be evaluated the following parameters as follow Weight variation (mg), Hardness, Thickness, Friability, Drug content uniformity, Floating lag time, the in vitro cumulative amount of drug released was shown the F4 is 99% within 12 Hours the comparative studies with marketed formulations F4 show the better results. In vitro release rate studies showed that the maximum drug release was observed F4 formulation up to 12 hours.