ANALYSIS OF MTHFR GENE GLU429ALA POLYMORPHISM SIGNIFICANCE IN THE RISK OF MYOCARDIAL INFARCTION.


Khamidov Diyorbek Abdullayevich, Ibragimov Dilshodbek Nabievich
Assistants of Andijan State Medical Institute, c. Andijan, Uzbekistan
Abstract
Alleles and haplotypes of the Glu429Ala polymorphism of the MTHFR gene did not affect the risk of developing MI. In all likelihood, the prothrombotic effect of polymorphisms of this gene can manifest itself when it is combined with other genetic mutations that affect the risk of developing MI or when a combination of hereditary and acquired factors is present. Such combinations are a much greater threat than the presence of one genetic disorder of the coagulation system.
Keywords: myocardial infarction, COVID-19, Glu429Ala genetic polymorphism of MTHFR gene.
Journal Name :
EPRA International Journal of Multidisciplinary Research (IJMR)

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Published on : 2024-04-29

Vol : 10
Issue : 4
Month : April
Year : 2024
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