A fever is an increase in body temperature above average, often due to the bodys response to infection. Antipyretic drugs such as paracetamol or ibuprofen are used to reduce fever. Red ginger, with compounds such as gingerol and shogaol, can also help relieve fever. Red ginger contains compounds such as gingerol and shogaol that have anti-inflammatory and antipyretic properties, helping to reduce fever and pain. Experimental studies using Post-Test Only Control Group Design were conducted to test the antipyretic and analgesic effects of Ginger extract (Zingiber officinale) on male Wistar rats. Acetic acid writhing test, body temperature evaluation, and hematology analysis were performed with IBM SPSS 25. The results showed a significant decrease in body temperature after 5 hours of administration, especially in the ginger extract -III group (600 mg/kg body weight). Hematological analysis also showed a significant decrease along with increasing doses of the extract. These results confirm the potential of Ginger (Zingiber officinale) as an antipyretic and analgesic agent that can be explained through active compounds such as gingerol and shogaol that have anti-inflammatory and analgesic effects. Ginger can be a natural alternative in managing fever and pain in traditional herbs and warm compresses, with potential effects comparable to conventional antipyretic and analgesic drugs.