The article presents the evolution of the introduction of digital technologies into the system of oncological screening, multimodal technologies of interventional radiology, statistical data on the growth of malignant neoplasms of the breast in the world and Russia, shows the advantages of digitalization of radiation diagnostics, interdisciplinary integration with systems biology omics technologies, contributing to the development of a new direction radiogenomics, and also pointed out the existing problems of introducing the latest technologies of interventional radiology, the need to train a multimodal specialist.