This research aims to determine the effect of innovative pop-up book learning media on improving students mathematical communication skills and mathematics learning interest. This research was conducted at Inpres Kayawu Elementary School. This research is using experimental method. Data collection techniques use tests and questionnaires whose validity and reliability have been tested. To determine the validity of each item, the Pearson Product Moment technique is used. Reliability testing is carried out on each item whose validity has been tested using the Cronbach Alpha technique. Data management in this research uses descriptive analysis, normality test, hypothesis I and II tests using the t test, hypothesis III test using the Manova test, and coefficient of determination (R²) test. The results of this research show that, 1) there is an influence of the use of pop-up book innovative learning media on mathematical communication skills in grade III students at Inpres Kayawu Elementary School, and 2) there is an influence of the use of pop-up book innovative learning media on mathematics learning interest grade III students at Inpres Kayawu Elementary School, and 3) there is an influence of the use of innovative pop-up book learning media on mathematical communication skills and mathematics learning interest in grade III students at Inpres Kayawu Elementary School