Ayurveda's primary need in the modern world is for its basic principles to be practically applicable. Research should be concentrated on all areas where scientific inputs can validate Ayurveda's tenets and philosophy. All substances are explained by Ayurveda in terms of five elements: Rasa, Guna, Virya, Vipaka, and Prabhav.Among these, Ayurveda and philosophy recognize one guna as the fundamental component of Srushti. All of the gunas have been given importance by Ayurveda so that they can be used to therapeutic practice. The improvement of treatment is contingent upon numerous aspects, of which Charaka has accorded primary significance to Paradi gunas. Paradi gunas are also known as the different attributes that pharmacists, doctors, and researchers must possess. According to Acharya Charaka, understanding of Paradi Gunas is necessary for "Sidhyupaya chikista," or the effective management of illness. The involvement of paradigunas in the selection, adaptation, and manifestation of drugs according to the patient's and the disease's situation is significant, especially for Desha and Kala. There are ten paradi gunas. Out of these Abhyas Guna is one of them. No treatment can occur without Abhyas. This Abhyas used by physicians and pharmacists in treating disease. Importance of Abhyas Guna by using Aushadha and regular therapy e.g Regular massage of Masha Saindhav Tail and regular intake of Rasna churna can be useful in Sandhivata. One can further understand the literary review of Paradi Gunas serves to explore the subject of the clinical practice.