Hepatitis, characterized by liver inflammation, poses significant health risks, including chronic liver disease and cancer. This case series explores the management of hepatitis through Ayurveda treatments, correlating the condition with Kamala Roga, which is associated with Pitta Dosha and Rakta Dushti. Two cases were treated using Ayurveda interventions, specifically Mridu Shodhana and Shamana Chikitsa, aimed at balancing Pitta Dosha and Shodhana of Rakta. Formulations such as Arogyavardhini Rasa, Patolakaturohinyadi Kashaya, and Tab Nirocil, along with dietary adjustments. The treatment resulted in significant clinical improvements, with notable reductions in total bilirubin, SGOT, and SGPT levels, indicating enhanced liver function and reduced inflammation. These outcomes suggest that classical Ayurveda treatments can offer a precise and effective therapeutic approach for Kamala with the help of Samprapti Vighatana Chikitsa.