COMPLETE STUDY FORMULATION OF EFFERVESCENT TABLET FROM CARICA PAPAYA, MORINGA AND AJWAIN IN DIABETIC
Dr Swati Rawat, Dr Sunil S Jaybhaye, Mr Gitesh V. Vyas, Ms Bhagyashri S. Gaikwad , Rushikesh Laxman Cheke
Institute of Pharmacy Badnapur, Jalna, Maharashtra
Abstract
Objectives: Studies show that papaya and bay leaf have significant medicinal properties, including the ability to help with degenerative diseases like diabetes. However, no herbal tablets combining these two plants have been made before. This research aimed to develop tablets using extracts from papaya and bay leaf, combined with different concentrations (1%, 2%, and 3%) of the binder polyvinylpyrrolidone (PVP) K30, prepared through the wet granulation method.
Methods: The tablets were evaluated for their physical properties, such as weight variation, friability (resistance to breaking), hardness, disintegration time, and appearance, using standard pharmaceutical methods. The total flavonoid content in the extracts was measured using a spectrophotometer.
Results: The tablets were light brown with flat surfaces, a specific smell, and a bitter taste. Their physical properties met pharmaceutical standards. The flavonoid content in papaya and bay leaf extracts was 1.562% and 2.240%, respectively.
Conclusions: PVP K-30 can effectively be used as a binder to produce high-quality, ready-to-use tablets from papaya and bay leaf extracts.
Keywords: Papaya extract, Bay leaf extract, Tablets, Polyvinylpyrrolidone K30, Flavonoid.
Journal Name :
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EPRA International Journal of Multidisciplinary Research (IJMR)
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Published on : 2024-11-21
Vol | : | 10 |
Issue | : | 11 |
Month | : | November |
Year | : | 2024 |