Ginger (Zingiber officinale) has long been used in traditional medicine for its therapeutic properties, including anti-inflammatory, antioxidant, anti-nausea, and analgesic effects. This abstract outlines various drug evaluation methods employed to assess the pharmacological properties, safety, and efficacy of ginger and its bioactive compounds. Methods such as in vitro assays, animal studies, clinical trials, and analytical techniques like high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS) are utilized to evaluate ginger’s potential in treating a range of ailments, including digestive disorders, pain, and inflammation. Additionally, the role of bioavailability and pharmacokinetics in ginger’s therapeutic effects is discussed. These evaluation methods help establish scientific validation for the medicinal use of ginger, support the standardization of its active constituents (e.g., gingerol), and guide the development of ginger-based pharmaceutical products. The abstract concludes by highlighting the need for further research to elucidate optimal dosing, long-term safety, and therapeutic efficacy in diverse populations.