This project focuses on the development and evaluation of pharmaceutical strategies for the treatment of brain tumors. It encompasses the formulation of novel drug delivery systems, such as nanoparticles and liposomes, to enhance the targeted delivery of chemotherapeutic agents to the brain. The study aims to overcome challenges like the blood-brain barrier, drug resistance, and systemic toxicity. Key findings include improved drug bioavailability, enhanced tumor specificity, and reduced side effects, demonstrating the potential of advanced drug delivery platforms in brain tumor therapy. The project concludes with recommendations for clinical translation and further research in personalized medicine