Sthoulya (Obesity) has been a growing global epidemic for decades, driven by lifestyle changes, poor dietary habits, and a decrease in physical activity. The global obesity rate continues to rise, and it is estimated that at least 2.8 million people die each year due to obesity. Additionally, 2.3% of the total global Disability-Adjusted Life Years are attributed to overweight and obesity-related conditions. A 34-year-old man had been struggling with obesity and associated symptoms, including constipation, loss of appetite, and a sensation of heaviness in his body. He also experienced symptoms of Amlapitta, such as severe burning sensation, belching, and nausea. The treatment plan for this patient involved a comprehensive approach, including Udwartana and Parisheka for five days, followed by Snehapana and Virechana to detoxify the body. Along with these treatments, the patient adhered to a specific Apatharpana diet, which was low in calories and fats, designed to regulate nourishment and reduce excess weight. The patient was also engaged in Yogasana practices and Vyayama to promote calorie expenditure and enhance fat metabolism. The overall treatment strategy was a holistic approach based on Nidana parivarjana, Shamanoushadhi, Shodhana, Pathyahara sevana, Vyayama, and behavioral therapies. As a result of this comprehensive approach, the patient's BMI significantly decreased, and he experienced marked improvements in both obesity and Amlapitta symptoms.