This study aimed to determine the influence of self-compassion and learners’ empowerment on students’ well-being among teacher education students at Kapalong College of Agriculture, Sciences and Technology (KCAST). This study utilized the regression analysis design utilizing correlational technique. The respondents of this study were 233 students mainly from first year to fourth year students under the Academic Year 2023-2024, first semester. The statistical data treatment used were mean to determine the level of self-compassion; the level of learners’ empowerment and the other was the level of students’ well-being. It also used a Pearson product moment correlation to measure the relationship between self-compassion and students’ well-being; learners’ empowerment and students’ well-being. Findings revealed that students’ overall level of self-compassion was generally at high level that means it was oftentimes manifested by the students, while the overall level of learners’ empowerment is also at high level of performance which means that it is oftentimes manifested and also the overall level of students’ well-being was generally at high level of performance which means that it is oftentimes manifested. On the other hand, the result revealed that both self-compassion and learners’ empowerment had high significant relationship on the students’ well-being which indicates that the self-compassion may affect the students’ well-being; when students have a sense of self-compassion, the students will tend to show kindness, understanding and care towards themselves even in times of challenges or life adversities. Moreover, when learners are empowered, they tend to enjoy what they are learning and that enjoyment will lead the students to a healthier life throughout their journey.