Background: Work-related musculoskeletal disorders (WMSDs) are a significant global occupational health issue, affecting workers across all industries, including automobile manufacturing. Employees in this sector face high risks of WMSDs, which can severely impact their physical and mental well-being. Objective: The objective of this study is to determine the prevalence of wrist and hand pain in automobile workers. Method: Articles were chosen from multiple platforms like Google Scholar, PubMed, SCISPACE, and ScienceDirect, spanning 2010-2023. Out of 35 articles, only 20 met the study's criteria for inclusion. Results: Wrist pain is a major concern for auto manufacturing workers globally. Factors like gender, age, physical activity, repetitive tasks, poor work environment, long hours, lack of training, and improper wrist posture are linked to WMSDs. These impact worker performance and cause economic losses. To reduce WMSD risk, mechanics should be trained in proper posture and the adoption of ergonomic devices and instruments during work tasks. Conclusion: Musculoskeletal disorders (MSDs) in hands and wrists are common in auto manufacturing and repair workers. Although wrist pain isn't as common as pain in other areas, it still contributes significantly to the overall musculoskeletal burden. Hence, it is vital to focus on prevention strategies such as incorporating ergonomic improvements and enhancing working conditions and the overall work environment to lower the occurrence of work-related MSDs. These strategies can help prevent work-related MSDs and promote the health and protection of these workers.