This study assesses the effectiveness and impact of the Community Empowerment through Science and Technology (CEST) program, focusing on its contributions to education, health and nutrition, water and sanitation, climate change mitigation, and livelihood. Data from 90 respondents provided insights into the program’s outcomes and sustainability. The findings show that the CEST program has notably improved educational access through digital libraries like STARBOOKS/VISSER and enhanced health and nutrition through community-based initiatives. It has also contributed to better water and sanitation, disaster risk reduction, and livelihood development, fostering economic growth and community well-being. The active participation of local government units (LGUs) was crucial to the program’s success, ensuring effective coordination and service delivery. Government funding was the most significant factor in the program’s success, while private sector involvement played a lesser role. Technical skills development and local engagement were strongly correlated with successful outcomes. The study concludes that sustained government investment, enhanced community participation, and stronger capacity-building are vital for expanding and ensuring the program’s future success. Recommendations include strengthening public-private partnerships, improving community engagement, and enhancing monitoring and evaluation frameworks.