Ayurveda, known as the mother of all medical sciences, encompasses a wealth of knowledge through its principles of health and healing. Acharya Sushruta made a remarkable contribution to the field of surgery by introducing the concept of Marma, or vital points in the body, which can be regarded as an ancient form of traumatology. These vital areas are extremely sensitive and susceptible to injury, potentially leading to severe pain, loss of function, or even fatal outcomes. Parshvasandhi Marma is one of the 107 vital points, with a pair located near the lower ends of the flanks, between the flanks and buttocks. Each measures about half an Angula and is categorized as a Sira Marma. Damage to this area can lead to internal bleeding and eventual death, classifying it as a Kalantara Pranahara Marma. This article provides details about the location, structural components, and measurements of the Parshvasandhi Marma Further more, the article delves into the serious consequences of trauma or injury to the Parshvasandhi Marma, emphasizing its critical role in sustaining life. It explains how damage to this highly sensitive and vital point can disrupt essential physiological functions, ultimately leading to fatal outcomes.