In Susruta Samhita 65 types of Mukha rogas are explained in total categorizing them under 7 Mukha avayavas respectively. Pittaja oshta roga is one among the 8 Oshta rogas explained by Acharya Susruta. A 35 year old patient presented with ulceration of lower lip associated with swelling, bleeding and burning sensation since 2 months. Patient had underwent many conventional treatments but does not have any permanent relief. In this patient Bahya lepa(applying of paste over lips) was chosen as main treatment modalitiy along with Guduchyadi kashayam, Grab capsule & Vaiswanara churnam internally. Along with aushadhi pathya ahara and vihara was advised like Dantasodhana, thikta rasa pradhana ahara and apathya ahara and vihara like mahisha ksheera sevana, tobacco chewing was advised to be avoided. The study concluded that after 3 weeks of above treatment patient got complete relief in all the symptoms with no reoccurrence of symptoms till last follow up.