This research delves into the multifaceted challenges and promising opportunities surrounding Intellectual Property Rights (IPR) in the realm of cloud computing, with a par- ticular emphasis on their impact on entrepreneurial ventures and technological innovation. As cloud-based solutions become indispensable to modern business ecosystems, especially for small and medium enterprises (SMEs), they introduce complex legal, technical, and operational hurdles in the protection, enforcement, and commercialization of intellectual assets. This study provides a thorough assessment of current IPR frameworks within cloud environments, scrutinizes the specific vulnerabilities faced by entrepreneurial innovators, and evaluates how cross-border legal discrepancies and the lack of harmonized global standards affect IPR management. Furthermore, it proposes strategic approaches for securing intellectual property in cloud systems, explores the broader implications for entrepreneurial initiatives seeking to capitalize on cloud technologies, and examines how these dynamics influence the balance between innovation and protection in a rapidly evolving digital landscape.