This study examined the instructional practices employed by teachers to assist students with Down syndrome in inclusive educational environments, taking into account their demographic and professional backgrounds. The participants, primarily seasoned teachers with extensive training in inclusive education, offered insights into the practical implementation and challenges of inclusive teaching methodologies. Research indicated that teachers utilize several tactics, including assistive technology, differentiated instruction, and peer cooperation. Nonetheless, personalized education surfaced as a domain needs additional enhancement, underscoring the want for more focused support and training. Participants regarded existing inclusive education policies and practices as significantly advantageous for the comprehensive development of learners with Down syndrome, especially in the academic, social, behavioral, and communicative spheres. Notwithstanding the hurdles faced during implementation, these impediments did not substantially undermine teachers' belief in the efficacy of inclusive education. Statistical study revealed significant variations in instructional approaches based on instructors' age, gender, experience, and training exposure, highlighting discrepancies that necessitate addressing through professional development. In light of these findings, the study proposed the "Inclusion Excellence Initiative," a comprehensive intervention program comprising intensive workshops, mentorship, online modules, and resource allocation to improve instructional consistency and quality. The program prioritizes ongoing assessment to guarantee its adaptability to the requirements of both educators and learners. The study emphasizes the necessity of ongoing teacher training, equal access to professional development, and institutional support to enhance inclusive practices. Recommendations encompass the execution of the planned effort and the enhancement of inclusive education policies to guarantee enduring and significant results for students with Down syndrome.