The article presents the results of clinical and functional assessment and effectiveness of complex medical rehabilitation in children with idiopathic scoliosis, muscular torticollis and spina bifida. The aim of the study was to develop and test personalized programs aimed at correcting biomechanical disorders, reducing neurological manifestations and improving the quality of life of patients. The study included 54 children distributed across nosological groups. Validated motor function assessment scales, electromyography data, visual analog scale (VAS) and the PedsQL quality of life questionnaire were used. The analysis revealed pronounced and moderate therapeutic effects from the implementation of a multi-level rehabilitation model, which confirms its clinical validity and the need for an interdisciplinary approach in pediatric rehabilitation.