Hospitalization often generates significant stress, anxiety, and emotional distress in children due to separation from family, unfamiliar environments, and medical procedures. Supporting their emotional well-being is a vital aspect of pediatric nursing practice, ensuring holistic care beyond physical recovery. Digital storytelling has emerged as a therapeutic and educational intervention that combines creativity, technology, and narrative expression. This approach allows children to articulate their experiences, cope with illness-related stressors, and regain a sense of agency. Nurses, as primary caregivers, are uniquely positioned to implement and facilitate digital storytelling interventions within pediatric settings. This article explores the role of digital storytelling as a nursing intervention to support emotional well-being in hospitalized children. It discusses the theoretical foundations, practical applications, benefits, challenges, and strategies for integrating storytelling into clinical care. Furthermore, it highlights the impact on children’s psychological resilience, communication with families, and overall patient outcomes. The review emphasizes the importance of training nurses in creative and digital modalities to foster a child-centered approach to care, aligning with holistic and family-centered nursing principles.