The art of repertorization in Homoeopathy has evolved through the works of stalwarts who provided structured approaches to clinical prescribing. Among them, William Boericke occupies a significant place through his Pocket Manual of Homoeopathic Materia Medica with Repertory. Boericke’s repertory, though comparatively concise, is distinctive in its clinical orientation. Unlike Kent’s philosophical structure or Boger’s analytical method, Boericke’s repertory emphasizes pathological conditions, clinical rubrics, and diagnostic groupings that directly relate to disease expressions. In daily clinical practice, a homoeopath often encounters cases where the individuality of the patient is less pronounced, and the pathology predominates. In such situations, Boericke’s repertory offers a practical tool, guiding the physician to remedies based on pathological generals, disease names, and characteristic modalities. This approach bridges the gap between the patient’s disease diagnosis and the remedy selection, making it particularly useful in acute, pathological, and therapeutic prescribing. Decoding pathological conditions using Boericke’s repertory provides a clinical lens to homoeopathic practice. It enables practitioners to translate pathological findings, diagnostic terms, and therapeutic hints into a repertorial framework. This strengthens both the accuracy of prescription and the physician’s confidence in handling acute and chronic pathological cases.