The re-emergence of Central Asia as a tactical backyard to the modern international relations has brought with it a fresh analytical focus on the bilateral and multilateral interactions that powers in the region and the world at large have with the states within the former Soviet space. Uzbekistan has become one of these, now especially consequential actors because of the position it holds at the geographical and political centre in Central Asia. Uzbekistan is a significant point in the strategic game of large power calculation due to its large population, a critical location in the middle of trans-regional connectivity routes, and a foreign policy that is increasingly liberalised to diversified external relationships since 2016, under the leadership of President Shavkat Mirziyoyev (Luzianin 2019; Rashid 2020). Here, India has acquired a commendable depth of involvement with Uzbekistan due to the convergence of interests comprising connectivity, counterterrorism, energy, trading, and similar needs necessitating to deal with an unstable regional environment, which is brought about by the re-entry of Taliban rule in Afghanistan.