Kriyakala, a cornerstone of Ayurvedic pathology, delineates the six progressive stages of disease evolution—from subtle doshic accumulation to complications. This framework surpasses modern pathology's focus on structural alterations by prioritizing functional imbalances for early intervention. Stages include Sanchaya, Prakopa, Prasara, Sthanasamshraya, Vyakti, and Bheda. This paper elucidates Kriyakala's role in early diagnosis, prevention, and integrative clinical practice, underscoring its relevance amid rising lifestyle disorders.