The article discusses the frequency of occurrence and clinical manifestations of stomatitis in patients after prosthetics with acrylic polymers. 48 patients aged from 42 to 88 years were examined. Among the surveyed persons there were 30 women and 18 men. All patients needed partial removable dentures. There were no contraindications to prosthetics. The prostheses were prepared from the acrylic polymer Etacril-02. Due to the urgency, there is a need to solve the medical and social problem and develop new technologies for the effective comprehensive treatment of patients with partial and complete absence of teeth