This research focused on use and effectiveness of teaching approach in science with regards to Most Essential Learning Com-petencies (MELCs) distribution in teaching Science.The descriptive method of research was used in this study to gather the necessary data and information on the Teaching Approach in Science, their Use and Effectiveness on Most Essential Learning Competencies (MELCs) Distribution. The goal of the researchers is to know the level of teaching approach in terms of en-hanced students’ learning experience, improved instructional management strategies, strengthened teaching standard, plan for variety of instructional strategies and level of MELCs distribution with regards to content standards, performance standards, topic sequence, topic time allotment, topic content and topic level of difficulty. The purpose of this study was to examine the sig-nificant effect of teaching approach to MELCs distribution. The information obtained by completing this study will beneficial to students, teachers, schools and DepEd officials. The results demonstrated that teaching approach have significant effect on MELCs or Most Essential Learning Competencies distribution in teaching science. The DepEd teachers are the recipients of this study