Self-esteem as a psychosocial factor that is likely to foretell outcomes like academics, happiness, marital satisfaction and relationships is also a construct that could lead to marital success and happiness. This study examined secondary school teachers’ self-esteem as a determinant of their marital adjustment in Anambra state. Three research questions were posed to guide the study while one null hypothesis was tested at a 0.05 level of significance. A correlational research design was adopted for the study. A sample size of 1,408 married teachers was drawn from a population of 6,987 married teachers. A multi-stage sampling procedure was followed in selecting the study sample. Two instruments: The marital Adjustment Scale (MAS), and Self- Esteem Scale (SES) were used for data collection. The instruments were duly validated by experts in measurement and evaluation and Guidance and Counselling. The reliability coefficient was established thus; 0.85 for the Self-esteem questionnaire, and 0.74 for the Marital Adjustment Questionnaire. Data was collected through a direct delivery approach and was analysed using SPSS version 23. Range of aggregate scores and Pearson correlation coefficients were used to answer research questions and while a t-test was used to test the hypotheses. Findings of the study showed among others there is a non-significant very low positive relationship existing between married teachers’ Self-esteem and their marital adjustment in secondary schools in Anambra State. Based on the study’s findings, it was suggested, among other things, that school Guidance Counsellors organise workshops and seminars for married teachers aimed at fostering healthy self-esteem for successful marital adjustment.