It should be noted that the history of Jizzakh region has been studied less than in other regions of the country for the last almost a quarter of a century. These circumstances and factors determine the relevance and necessity of the topic. All schools operating in the country have their own history, their own way of growth. Our article tells about the history of the formation of secondary schools in Jizzakh, the stages of development, the life and work of dedicated teachers who worked in them. There is also talk about statesmen, representatives of culture and art, industrialists, loyal sons of our people, who grew up in educational institutions in the region. This article describes the private schools that teach reading and writing in accordance with the requirements of the time, schoolteachers, people who built science schools at their own expense, scholars of their time, the development of education in the country, the closure of old schools in towns and villages and their bases, the beginning of the establishment of new schools, the literacy of adults and young people in schools, as well as the conduct of cultural and educational work among teachers in the community.