Background The COVID-19 pandemic ushers in a “new” normal, in which digitization implements different ways of working and learning. The aim of the study was to assess the perceived impact of online classes on sophomore nursing students of Santiago City. Method: In this descriptive cross-sectional study, 118 sophomore nursing students (n=118) were recruited. An online survey questionnaire was the main tool to collect data. Descriptive statistics were employed for data analysis. Result: The majority of respondents were female (79.66%), and perceived skills and competencies of instructors during online class, weighted in different areas such as instructional skills (M=3.48, SD=1.15), instructional resources (M=3.45, SD=1.15), approaches/techniques (M=3.38, SD=1.18) and evaluation techniques (M=3.37, SD=1.14) which interpreted as satisfactory respectively in all areas. Lastly, the perception of the respondents on the effects of online classes shows a strong agreement on the belief that face-to-face learning is more effective than online learning. Conclusion: Nowadays, the new normal continues to shape the world. With its use, few students find their lives easier, more convenient, and more comfortable. But most students face a dilemma in utilizing new normal technology in making school requirements which did not help them to be productive.