Natural polymers are one of the important scopes of pharmaceutical formulation as they provide various precedence over synthetic polymers like they are biodegradable, non-toxic, biocompatible, and easily available. There are various natural polymers available like collagen, fibrinogen, soya protein, polysaccharide, starch, chitin, alginate, chitosan, agar, and zein. Similarly, this present review will focus on biopolymer and their probable pharmaceutical uses. As per the detailed literature search, it has been found that naturally available biopolymers are having multiple pharmaceutical applications along with pharmacological activities and advantages, above mentions polymers composition, origin, uses and activities and future uses are discussed in detail in this review. This review also focuses on the use of the biopolymers in different types of covering in the tablets formulation