Chronic respiratory diseases, which began in childhood, are the cause of disability not only for children, but also for the adult population. Thus, according to the latest data, the incidence of obstructive pulmonary disease has increased by 3.2 times. Some mechanisms for the development of their progression in children have not been fully disclosed. In recent years, the number of antibiotic-resistant strains of microorganisms has increased, which contributes to the progression of lung tissue damage and worsens the prognosis of the disease. In solving the problem of the rationality of antibiotic therapy, an extremely important place is occupied by the issue of creating effective therapeutic concentrations of an antibiotic in a chronic focus of pulmonary inflammation. The effect of antimicrobial therapy is determined not only by the correct choice of the drug, but also by the method, its dose and frequency of administration. One of the effective methods that improve the results of treatment is physiotherapy procedures used in the complex treatment of CLD.